Thursday, August 12, 2021

The Covid-19 virus, mutation and vaccines

 

The Covid-19 virus, mutation and vaccines

The Covid-19 virus or Corona Virus does not show in human faeces, blood, and urine. Thus tests could not be done from them.  That means the virus is only at the nasal/sinus/throat cavities and lungs. Covid-19 vaccines are injected and could take 5 to 10 minutes to take effect.  Why?  Because the vaccine has to circulate around the body and there is no assurance it will adhere to the nasal cavities and lung cells. (Please note: Aside from the foregoing introduction above, the information below are sourced on items/articles available on the internet)

How long does an IM injection take to kick in?

"Intramuscular administration relies upon the high vascularity of muscle tissue to achieve a moderately rapid onset of action, usually within 5 to 10 minutes."

Which drug route has the fastest action?

"The intravenous route is considered to be the fastest route of drug administration. The injections and the infusions are administered by this route have 100% bioavailability."

Inhaler or intranasal spray as COVID-19 vaccine will be better

https://www.sciencedaily.com/releases/2021/07/210708135321.htm

"Unlike traditional vaccines that require an injection, this vaccine is administered through a nasal spray similar to those commonly used to vaccinate against influenza. The vaccine used in the study only requires a single dose and it may be stored at normal refrigerator temperatures for up to at least three months. Because it is given intranasally, the vaccine may also be easier to administer, especially for those who have a fear of needles."

About Covid-19 mutation

https://www.who.int/news-room/feature-stories/detail/the-effects-of-virus-variants-on-covid-19-vaccines?gclid=EAIaIQobChMItfO9u4ar8gIVl3ZgCh1nXQrfEAAYASAAEgKky_D_BwE

https://www.osfhealthcare.org/blog/how-covid-19-mutates-and-how-it-affects-vaccines/

“This perpetual cycle goes on of constant replication. Each time a replication occurs, there is a small chance that code could change. When you have this go over a huge population over time, the odds start to favor that the virus will adjust. It’s evolution on a very, very rapid level.”

"So it’s not surprising that a virus like SARS-CoV-2, the virus that causes COVID-19, would mutate. That’s something scientists and vaccine developers have expected since the beginning of the current epidemic."

"The question is how drastically and quickly is the virus changing."

https://www.sciencedaily.com/releases/2021/07/210708135321.htm

"For SARS-CoV-2, scientists estimate that one mutation becomes established in the population every 11 days or so. But this process may not always happen at a steady pace."